Statistics Seminar: Terry Speed -- Correcting for Unwanted Variation in Microarray Data

Terry Speed Division of Bioinformatics, The Walter & Eliza Hall Institute of Medical
Research Department of Statistics, University of California at Berkeley 

Location: Carslaw 173 

Time: 2pm Friday, May 14, 2010 

Title: Correcting for Unwanted Variation in Microarray Data 

Abstract: Principal components have been used a lot with microarray data to exhibit
unwanted variation, and to some extent to remove such variation.  Such efforts are also
called normalization.  In this talk I will review some of these methods, and related
work, and propose a simple but apparently novel variant which works a lot of the time,
though not always.  Part of my story will be a discussion of how one tells whether one
is helping or hurting the analysis by adjusting.  

Joint work with Johann Gagnon-Bartsch