One School Seminar: "Viewing snapshots of the cellular landscape of diseased tissue through the lens of a statistician" Ellis Patrick (University of Sydney) Thursday 18 May, 1-2pm Quad S249 & online via Zoom - https://uni-sydney.zoom.us/j/84918847505 Abstract: The human body comprises over 37 trillion cells with diverse forms and functions, which can exhibit dynamic changes based on their environmental context. Understanding the spatial interactions between cells and changes in their state within the tissue microenvironment is crucial to comprehending the development of human diseases. State-of-the-art technologies can now deeply phenotype cells in their native environment, providing a high-throughput means of identifying spatially related changes in their function. In this talk, I will illustrate how established statistical tools can be bent in novel ways to produce new perspectives of diseased tissue. By doing this I hope to motivate discussions on how these complex cellular systems could be quantified with unique, robust or mathematically rigorous approaches. ----------- Join us afterwards for SMRI afternoon tea, held Thursdays 2:00-2:45pm on the SMRI Terrace (weather permitting, otherwise held in the SMRI Common Room - A14-04-L4.37).